MyBioSource.com's TCF3 Antibody is a Mouse monoclonal antibody. The TCF3 Antibody was generated using E2A, E47, ITF1, TCF3, and VDIR as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, and Western Blot.
Description
Background: Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer